Every person is unique and it is therefore difficult to say what you will notice first. Most people notice that their skin becomes much softer, any dryness disappears and if they have a serious skin condition, like eczema, the major improvements can be seen in as little as a week. However, the slightly longer-term changes, like more energy, improved thinking and concentration as well as an improvement in handling stress and increased immunity, may take from a few weeks to a few months to become noticeable. Remember that your body has to start the process of replacing each and every membrane with the right fats, so the changes cannot be overnight.